An introduction to effective use of enrichment analysis software

Abstract

Abstract In recent years, there has been an explosion in the range of software available for annotation enrichment analysis. Three classes of enrichment algorithms and their associated software implementations are introduced here. Their limitations and caveats are discussed, and direction for tool selection is given.

Keywords

• software
• enrichment
• gene enrichment analysis
• GSEA
• pathway analysis
• gene ontology
• gene list