Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes

• Anirban Maitra,
• Alexandre Reuben,
• Chantale Bernatchez,
• Marie-Andree Forget,
• Donastas Sakellariou-Thompson,
• Tina Cascone,
• Annikka Weissferdt,
• Jianjun Zhang,
• Boris Sepesi,
• Ignacio Wistuba,
• Ara A Vaporciyan,
• Marcelo V Negrao,
• Lorenzo Federico,
• John V Heymach,
• Don L Gibbons,
• Cara L Haymaker,
• Junya Fujimoto,
• Jack A Roth,
• Parin Shah,
• Peixin Jiang,
• Roohussaba Khairullah,
• Yan Long,
• Shiaw-Yih Lin,
• Meredith L Frank,
• Chantal Alexia Neutzler,
• Chi-Wan B Chow,
• Kyle Gregory Mitchell,
• Daniel J McGrail

Affiliations

Anirban Maitra

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Alexandre Reuben

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Chantale Bernatchez

Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Marie-Andree Forget

Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Donastas Sakellariou-Thompson

Biologics Development, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Tina Cascone

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Annikka Weissferdt

Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Jianjun Zhang

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Boris Sepesi

Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Ignacio Wistuba

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Ara A Vaporciyan

Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Marcelo V Negrao

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Lorenzo Federico

Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

John V Heymach

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Don L Gibbons

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Cara L Haymaker

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Junya Fujimoto

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Jack A Roth

Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Parin Shah

Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Peixin Jiang

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Roohussaba Khairullah

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Yan Long

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Shiaw-Yih Lin

Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Meredith L Frank

Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Chantal Alexia Neutzler

Biologics Development, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Chi-Wan B Chow

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Kyle Gregory Mitchell

Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Daniel J McGrail

Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA