Human Nutrition & Metabolism (Jun 2023)

The interlink between climate changes, gut microbiota, and aging processes

  • William Ben Gunawan,
  • Muhammad Naufal Putra Abadi,
  • Farhan Syafiq Fadhillah,
  • Fahrul Nurkolis,
  • Adriyan Pramono

Journal volume & issue
Vol. 32
p. 200193

Abstract

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The world's weather is constantly shifting and increasingly unpredictable. Climate change was also shown to influence human health and both soil and gut microbiome. These changes may also affect the human aging process, which is connected to multidimensional aspects ranging from health, economy, and psychology. As a result, the purpose of this review is to examine the relationship between aging, gut microbiota, and climate change. This discussion aims to increase awareness of the inevitable change in aging physiology and gut microbiota composition that is caused by climate change by tying together the environmental and clinical health elements. This review will also support the evidence for the link between environmental problems and public health problems. The main findings of this review found that human aging and gut microbiota had a bidirectional relationship. The change in one matter influences the other, which may be instigated by climate change. Moreover, climate change also influences the soil microbiome, which is indirectly related to the quality of the crops that will further act as nutritional factors that shift the composition of human gut microbiota. Various modulation mechanisms of gut microbiota in aging domains were also explored. The review was concluded by proposing a model and underlining some implications that need to be further addressed.

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