Sonographic Evaluation of Splenic Dimensions in Healthy Pregnant and Non-Pregnant Women

Abstract

Objective: To compare the ultrasonographic findings of splenic dimension in healthy pregnant and non-pregnant women. Methods: This analytical cross-sectional study was conducted at University Ultrasound Clinic, Lahore from August 2022 to February 2023. A total of 200 females (100 non-pregnant and 100 pregnant) were examined. Mindray and Toshiba Ultrasound Machines were used to perform the ultrasonography. The measurements of splenic length, width, and thickness were recorded. The length of the spleen was measured in a longitudinal view. The width of the spleen was measured in a transverse view. The anteroposterior diameter (thickness) of the spleen was also measured. Results: The overall mean age was 29.0 ± 7.8 years. The mean difference of splenic width, thickness, and volume were significantly higher in pregnant women as compared to non-pregnant women i.e., 5.58 ± 1.44 cm vs. 5.15 ± 1.42 cm (p-value 0.033), 6.37 ± 2.56 cm vs. 4.46 ± 1.10 cm (p-value <0.001), and 178.2 ± 97.90 cm³ vs. 118.8 ± 47.57 cm³ (p-value <0.001) respectively. A significant difference of splenic width (p-value <0.001) and thickness (p-value <0.001) were observed with respect to gestational age of the individuals. Moreover, mean difference of splenic width was significantly increased in age group 15-30 years as compared to 31-51 years i.e., 5.68 ± 2.25 cm vs. 4.94 ± 2.00 cm (p-value 0.022) respectively. Conclusion: In pregnancy, the splenic thickness and splenic volume is seen to be increased when compared to non-pregnant women.

Keywords

• Gestational Age
• Maternal, Obstetrics
• Pregnancy
• Spleen
• Ultrasound