Smoking, haptoglobin and fertility in humans

N Bottini; A Magrini; J MacMurray; E Cosmi; M Nicotra; F Gloria-Bottini; A Bergamaschi

doi:10.1186/1617-9625-1-1-3

Tobacco Induced Diseases (Mar 2002)

Smoking, haptoglobin and fertility in humans

N Bottini,
A Magrini,
J MacMurray,
E Cosmi,
M Nicotra,
F Gloria-Bottini,
A Bergamaschi

Affiliations

N Bottini: The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
A Magrini: Division of Occupational Health Medicine, Department of Biopathology and Imaging Diagnostics, University of Rome, Tor Vergata, School of Medicine, Rome, Italy
J MacMurray: Department of Medical Genetics, City of Hope National Medical Center, Duarte, California
E Cosmi: Institute of Obstetrics and Gynecology, University of Rome La Sapienza, School of Medicine, Rome, Italy
M Nicotra: Institute of Obstetrics and Gynecology, University of Rome La Sapienza, School of Medicine, Rome, Italy
F Gloria-Bottini: Division of Medical Statistics, Department of Biopathology and Imaging Diagnostics, University of Rome Tor Vergata, School of Medicine, Rome, Italy
A Bergamaschi: Division of Occupational Health Medicine, Department of Biopathology and Imaging Diagnostics, University of Rome, Tor Vergata, School of Medicine, Rome, Italy

DOI: https://doi.org/10.1186/1617-9625-1-1-3
Journal volume & issue: Vol. 1, no. March

Abstract

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A prospective study on two samples of consecutive puerperae (total n° 667) from two populations has been carried out in order to investigate the possible effect of smoking habit on relationship between fertility and haptoglobin phenotype. In both populations the negative association previously reported between age of pueperae and Haptoglobin *1/*1 phenotype is present only in women with smoking habit pointing to an interaction between Hp and smoke on human fertility. This suggests that the effects of smoke on fertility are dependent on the Hp phenotype.

Published in Tobacco Induced Diseases

ISSN: 1617-9625 (Online)
Publisher: European Publishing
Country of publisher: Greece
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://www.tobaccoinduceddiseases.org

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Abstract

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