Superenhancer–transcription factor regulatory network in malignant tumors

Abstract

This study aims to identify superenhancer (SE)–transcriptional factor (TF) regulatory network related to eight common malignant tumors based on ChIP-seq data modified by histone H3K27ac in the enhancer region of the SRA database.

Keywords

• malignant tumors
• super enhancers
• transcription factors
• chip-seq
• rna-seq
• core regulatory circuitry
• superenhancer–transcription factor regulatory network