Industrial Hemp (<i>Cannabis sativa</i> L.) Inflorescences as Novel Food: The Effect of Different Agronomical Practices on Chemical Profile

Mattia Spano; Giacomo Di Matteo; Cinzia Ingallina; Anatoly Petrovich Sobolev; Anna Maria Giusti; Giuliana Vinci; Silvia Cammarone; Carola Tortora; Lara Lamelza; Sabrina Antonia Prencipe; Laura Gobbi; Bruno Botta; Federico Marini; Enio Campiglia; Luisa Mannina

doi:10.3390/foods11223658

Foods (Nov 2022)

Industrial Hemp (<i>Cannabis sativa</i> L.) Inflorescences as Novel Food: The Effect of Different Agronomical Practices on Chemical Profile

Mattia Spano,
Giacomo Di Matteo,
Cinzia Ingallina,
Anatoly Petrovich Sobolev,
Anna Maria Giusti,
Giuliana Vinci,
Silvia Cammarone,
Carola Tortora,
Lara Lamelza,
Sabrina Antonia Prencipe,
Laura Gobbi,
Bruno Botta,
Federico Marini,
Enio Campiglia,
Luisa Mannina

Affiliations

Mattia Spano: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Giacomo Di Matteo: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Cinzia Ingallina: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Anatoly Petrovich Sobolev: Magnetic Resonance Laboratory “Segre-Capitani”, Institute for Biological Systems, CNR, Via Salaria Km 29.300, 00015 Monterotondo, Italy
Anna Maria Giusti: Department of Experimental Medicine, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Giuliana Vinci: Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy
Silvia Cammarone: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Carola Tortora: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Lara Lamelza: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Sabrina Antonia Prencipe: Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy
Laura Gobbi: Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy
Bruno Botta: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Federico Marini: Department of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Enio Campiglia: Department of Agricultural and Forest Sciences, University of Tuscia, Via San Camillo de Lellis Snc, 01100 Viterbo, Italy
Luisa Mannina: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy

DOI: https://doi.org/10.3390/foods11223658
Journal volume & issue: Vol. 11, no. 22
p. 3658

Abstract

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In this study, the effect of several agronomical practices on the chemical composition of hemp inflorescences, a potential novel food that needs to be further studied, was observed. Here, the case study of inflorescences from Ferimon cultivars is discussed and submitted to different agronomical practices (irrigation and fertilizers) in different years, and the inflorescences harvested in different periods were analyzed by a multimethodological approach. Targeted and untargeted methodologies allowed cannabinoids, total phenolic content, metabolite profile and antioxidant activity to be determined. The biomass and inflorescence yields were also reported. The whole data set was submitted to ANOVA-simultaneous component analysis. The statistic results allowed us to observe that irrigation was responsible for the (–)-Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) increment. THC, cannabichromene (CBC), cannabigerol (CBG), succinate, and fructose resulted as higher in full female flowering than in the period of seed maturity. On the other hand, nitrogen supplementation led to an increase of iso-leucine, valine, and threonine. The obtained results underlined both the potential food application of hemp inflorescences, due to the rich chemical profile, and the strong effect of agronomical practices, mainly irrigation and harvesting, on the qualitative and quantitative characteristics of its metabolite profile.

Published in Foods

ISSN: 2304-8158 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology: Chemical technology
Website: http://www.mdpi.com/journal/foods

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