Nature Communications (Jul 2022)

Synthetic phosphoethanolamine-modified oligosaccharides reveal the importance of glycan length and substitution in biofilm-inspired assemblies

  • Theodore Tyrikos-Ergas,
  • Soeun Gim,
  • Jhih-Yi Huang,
  • Sandra Pinzón Martín,
  • Daniel Varón Silva,
  • Peter H. Seeberger,
  • Martina Delbianco

DOI
https://doi.org/10.1038/s41467-022-31633-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 8

Abstract

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The phosphoethanolamine modified cellulose in E. colibiofilms has revealed that polysaccharide functionalization alters the biofilm properties. Here, the authors show a model system to explore the role of phosphoethanolamine and other unnatural modifications on the properties of the biofilm-inspired assemblies.