Reversible Pulmonary Hypertension Associated with Myasthenia Gravis

Abstract

Myasthenia gravis (MG) is an autoimmune disease that causes localized and generalized muscle weakness caused by antibodies targeting various components of the postsynaptic membrane. Respiratory muscle involvement as a feared complication of this disease can be life-threatening and cause respiratory failure requiring intubation and mechanical ventilation. The relationship between MG and pulmonary hypertension (PH) has been rarely seen in the literature, and here we present a case who presented with respiratory failure and started treatment with the diagnosis of PH and was diagnosed with MG in the follow-up.

Keywords

• myasthenia gravis
• neuromuscular disease
• pulmonary hypertension