Cytomegalovirus proctitis as a complication of COVID-19 with immunosuppressive treatments

François Maillet; Annabelle Pourbaix; Diane le Pluart; Laura Sirmai; Speranta Andreea Postolache; Anne Couvelard; Nadhira Houhou-Fidouh; Lisa Males; Laurène Deconinck; François-Xavier Lescure

IDCases (Jan 2021)

Cytomegalovirus proctitis as a complication of COVID-19 with immunosuppressive treatments

François Maillet,
Annabelle Pourbaix,
Diane le Pluart,
Laura Sirmai,
Speranta Andreea Postolache,
Anne Couvelard,
Nadhira Houhou-Fidouh,
Lisa Males,
Laurène Deconinck,
François-Xavier Lescure

Affiliations

François Maillet: Infectious Diseases Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France; Corresponding authors.
Annabelle Pourbaix: Infectious Diseases Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France; Corresponding authors.
Diane le Pluart: Infectious Diseases Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France
Laura Sirmai: Hepatogastroenterology Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France
Speranta Andreea Postolache: Pathology Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France
Anne Couvelard: Pathology Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France
Nadhira Houhou-Fidouh: Virology Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France
Lisa Males: Radiology Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France
Laurène Deconinck: Infectious Diseases Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France; Corresponding authors.
François-Xavier Lescure: Infectious Diseases Department, AP-HP Bichat Claude-Bernard Hospital, 75018, Paris, France

Journal volume & issue: Vol. 24
p. e01111

Abstract

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We report a case of reactivated biopsy-proven cytomegalovirus proctitis complicating the course of severe COVID-19 pneumonia treated with dexamethasone, anakinra and lopinavir/ritonavir. No other contributing factor was found than iatrogenic immunosuppression and COVID-19 immune dysregulation. We draw attention to the immunosuppressive risk when treating severe COVID-19 pneumonia with immunomodulators.

Published in IDCases

ISSN: 2214-2509 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: http://www.journals.elsevier.com/idcases/

About the journal

Abstract

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