Medical Devices: Evidence and Research (May 2024)
Review of Evidence Supporting the Arista™ Absorbable Powder Hemostat
Abstract
Kristopher S LyBarger Sarah Cannon Cancer Center – HCA MidAmerica, Kansas City, MO, USACorrespondence: Kristopher S LyBarger, Sarah Cannon Cancer Center – HCA MidAmerica, 2340 East Meyer Bld, Suite 546, Kansas City, Mo, 64132, USA, Email [email protected]: Uncontrolled and diffuse bleeding is a dreaded event during open and laparoscopic surgery that may lead to postoperative complications, obstruction of the surgical field that reduces visualization, and prolonged operating times. Powder hemostats can be used to control bleeding and are easy to use, have a safe profile, and can achieve broad coverage area at a low cost.Methods: A strategic literature search of peer-reviewed, English language studies was conducted to capture evidence on the clinical efficacy and safety of a Microporous Polysaccharide Hemosphere (MPH) based Hemostat (Arista™ Absorbable Hemostat (Arista™ AH)).Results: Six preclinical studies were found which supported the use of MPH in various animal models of laparoscopic and open surgery, all of which demonstrated its safety and efficacy. Five single-arm and 11 comparative clinical studies similarly supported the efficacy and safety of MPH in various surgery types, including cardiac, renal, and dermatologic surgery.Conclusion: Published evidence supports the safe and effective use of MPH across a variety of surgical settings.Keywords: bleeding, hemostats, Arista™, surgery
