Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of spontaneous generation of infectious amyloids by patterned configurational change in host precursors in Creutzfeldt-Jacob disease.

Abstract

Transthyretin amyloidosis. Infectious amyloid proteins. Unconventional slow virus diseases. Spongiform encephalopathies. Genetic control and point mutations.