Frontiers in Neurology (Apr 2021)

Timing and Spectrum of Neurological Complications After Flow Diverter Implantation for Intracranial Aneurysms

  • Guillaume Charbonnier,
  • Jean-Philippe Desilles,
  • Simon Escalard,
  • Benjamin Maier,
  • Gabriele Ciccio,
  • Stanislas Smajda,
  • Robert Fahed,
  • François Delvoye,
  • Hocine Redjem,
  • Raphaël Blanc,
  • Michel Piotin,
  • Mikael Mazighi

DOI
https://doi.org/10.3389/fneur.2021.590383
Journal volume & issue
Vol. 12

Abstract

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Background and Purpose: The aim of this study was to characterize neurological complications after flow diverter (FD) treatment on a long follow-up cohort and identify predictive factors associated with these complications.Methods: This study was conducted on a monocentric cohort of patients treated for intracranial aneurysms by FD.Results: Between September 2008 and July 2018, 413 patients were treated for 514 aneurysms: 18% of the patients presented with at least one neurological complication during a median follow-up of 446 days (IQR 186–1,210). Sixty-one patients presented with ischemic complications, 13 with hemorrhagic ones and 10 with compressive processes. Among 89 neurological complications 64.5% were peri-operative (occurring within the 30 days following the procedure) and 35.5% were delayed after 1 month.Conclusions: Overall, neurological complications after FD implantation were overrepresented by cerebrovascular ischemic events occurring during the peri-operative period, but also in a delayed manner after 1 year. Long-term follow-up is relevant after aneurysm intervention using FD.

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