Journal of Lipid Research (Jan 2009)
Update of the LIPID MAPS comprehensive classification system for lipids1
- Eoin Fahy,
- Shankar Subramaniam,
- Robert C. Murphy,
- Masahiro Nishijima,
- Christian R.H. Raetz,
- Takao Shimizu,
- Friedrich Spener,
- Gerrit van Meer,
- Michael J.O. Wakelam,
- Edward A. Dennis
Affiliations
- Eoin Fahy
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Shankar Subramaniam
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Robert C. Murphy
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Masahiro Nishijima
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Christian R.H. Raetz
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Takao Shimizu
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Friedrich Spener
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Gerrit van Meer
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Michael J.O. Wakelam
- San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Edward A. Dennis
- To whom correspondence should be addressed; San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093-0505; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0505; Department of Chemistry and Biochemistry and Department of Pharmacology of the School of Medicine, University of California, San Diego, La Jolla, CA 92093-0505; Department of Pharmacology, University of Colorado Denver, Aurora, CO 80045-0598; National Institute of Health Sciences, Setagaya-ku, Tokyo 158-8501, Japan; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; Department of Molecular Biosciences, University of Graz, 8010 Graz, Austria; Bijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands; The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom
- Journal volume & issue
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Vol. 50
pp. S9 – S14
Abstract
In 2005, the International Lipid Classification and Nomenclature Committee under the sponsorship of the LIPID MAPS Consortium developed and established a “Comprehensive Classification System for Lipids” based on well-defined chemical and biochemical principles and using an ontology that is extensible, flexible, and scalable. This classification system, which is compatible with contemporary databasing and informatics needs, has now been accepted internationally and widely adopted. In response to considerable attention and requests from lipid researchers from around the globe and in a variety of fields, the comprehensive classification system has undergone significant revisions over the last few years to more fully represent lipid structures from a wider variety of sources and to provide additional levels of detail as necessary. The details of this classification system are reviewed and updated and are presented here, along with revisions to its suggested nomenclature and structure-drawing recommendations for lipids.
