Journal of Biological Research (Dec 2003)

Maize Based Diets and Mouse-Killing Behavior in Rats

  • M. Ernandes,
  • M. La Guardia,
  • M. Giammanco

DOI
https://doi.org/10.4081/jbr.2003.10555
Journal volume & issue
Vol. 79, no. 1

Abstract

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Mouse-killing behavior is correlated with decrease in brain serotonergic tone, caused by injection of p- chlorophenylalanine (which blocks serotonin synthesis), or by tryptophan free diets,which slow down serotonin production because source of tryptophan is done only by endogenous proteins.Another experimental method is maize exclusive diet:maize is, among cereals, that one which has the lowest tryptophan content, and the lowest value of the ratio between tryptophan and its concurrent amino acids for neuron access. In a lot of experiments, maize based diets gave rise to brain serotonin deficiency and to mouse-killing behavior in previous non killer rats.