Nature Communications (Sep 2018)

The MinDE system is a generic spatial cue for membrane protein distribution in vitro

  • Beatrice Ramm,
  • Philipp Glock,
  • Jonas Mücksch,
  • Philipp Blumhardt,
  • Daniela A. García-Soriano,
  • Michael Heymann,
  • Petra Schwille

DOI
https://doi.org/10.1038/s41467-018-06310-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 16

Abstract

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The E. coli MinCDE system oscillates between cell poles to position the main division protein FtsZ. Here authors use in vitro reconstitution to show that MinDE oscillations also regulate unrelated membrane proteins spatiotemporally into patterns and gradients by forming a moving physical barrier.