World Journal of Emergency Surgery (Feb 2019)
2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients
- Massimo Sartelli,
- Stefano Di Bella,
- Lynne V. McFarland,
- Sahil Khanna,
- Luis Furuya-Kanamori,
- Nadir Abuzeid,
- Fikri M. Abu-Zidan,
- Luca Ansaloni,
- Goran Augustin,
- Miklosh Bala,
- Offir Ben-Ishay,
- Walter L. Biffl,
- Stephen M. Brecher,
- Adrián Camacho-Ortiz,
- Miguel A. Caínzos,
- Shirley Chan,
- Jill R. Cherry-Bukowiec,
- Jesse Clanton,
- Federico Coccolini,
- Maria E. Cocuz,
- Raul Coimbra,
- Francesco Cortese,
- Yunfeng Cui,
- Jacek Czepiel,
- Zaza Demetrashvili,
- Isidoro Di Carlo,
- Salomone Di Saverio,
- Irina M. Dumitru,
- Christian Eckmann,
- Edward H. Eiland,
- Joseph D. Forrester,
- Gustavo P. Fraga,
- Jean L. Frossard,
- Donald E. Fry,
- Rita Galeiras,
- Wagih Ghnnam,
- Carlos A. Gomes,
- Ewen A. Griffiths,
- Xavier Guirao,
- Mohamed H. Ahmed,
- Torsten Herzog,
- Jae Il Kim,
- Tariq Iqbal,
- Arda Isik,
- Kamal M. F. Itani,
- Francesco M. Labricciosa,
- Yeong Y. Lee,
- Paul Juang,
- Aleksandar Karamarkovic,
- Peter K. Kim,
- Yoram Kluger,
- Ari Leppaniemi,
- Varut Lohsiriwat,
- Gustavo M. Machain,
- Sanjay Marwah,
- John E. Mazuski,
- Gokhan Metan,
- Ernest E. Moore,
- Frederick A. Moore,
- Carlos A. Ordoñez,
- Leonardo Pagani,
- Nicola Petrosillo,
- Francisco Portela,
- Kemal Rasa,
- Miran Rems,
- Boris E. Sakakushev,
- Helmut Segovia-Lohse,
- Gabriele Sganga,
- Vishal G. Shelat,
- Patrizia Spigaglia,
- Pierre Tattevin,
- Cristian Tranà,
- Libor Urbánek,
- Jan Ulrych,
- Pierluigi Viale,
- Gian L. Baiocchi,
- Fausto Catena
Affiliations
- Massimo Sartelli
- Department of Surgery, Macerata Hospital
- Stefano Di Bella
- Infectious Diseases Department, Trieste University Hospital
- Lynne V. McFarland
- Medicinal Chemistry, School of Pharmacy, University of Washington
- Sahil Khanna
- Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic
- Luis Furuya-Kanamori
- Research School of Population Health, Australian National University
- Nadir Abuzeid
- Department of Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University
- Fikri M. Abu-Zidan
- Department of Surgery, College of Medicine and Health Sciences, UAE University
- Luca Ansaloni
- Department of General Surgery, Bufalini Hospital
- Goran Augustin
- Department of Surgery, University Hospital Centre Zagreb and School of Medicine, University of Zagreb
- Miklosh Bala
- Trauma and Acute Care Surgery Unit, Hadassah Hebrew University Medical Center
- Offir Ben-Ishay
- Department of General Surgery, Rambam Health Care Campus
- Walter L. Biffl
- Trauma and Acute Care Surgery, Scripps Memorial Hospital La Jolla
- Stephen M. Brecher
- Pathology and Laboratory Medicine, VA Boston Healthcare System, West Roxbury MA and BU School of Medicine
- Adrián Camacho-Ortiz
- Department of Internal Medicine, University Hospital, Dr. José E. González
- Miguel A. Caínzos
- Department of Surgery, University of Santiago de Compostela
- Shirley Chan
- Department of General Surgery, Medway Maritime Hospital
- Jill R. Cherry-Bukowiec
- Department of Surgery, Division of Acute Care Surgery, University of Michigan
- Jesse Clanton
- Department of Surgery, West Virginia University Charleston Division
- Federico Coccolini
- Department of General Surgery, Bufalini Hospital
- Maria E. Cocuz
- Faculty of Medicine, Transilvania University, Infectious Diseases Hospital
- Raul Coimbra
- Riverside University Health System Medical Center and Loma Linda University School of Medicine
- Francesco Cortese
- Emergency Surgery Unit, San Filippo Neri’s Hospital
- Yunfeng Cui
- Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University
- Jacek Czepiel
- Department of Infectious Diseases, Jagiellonian University, Medical College
- Zaza Demetrashvili
- Department of Surgery, Tbilisi State Medical University, Kipshidze Central University Hospital
- Isidoro Di Carlo
- Department of Surgical Sciences, Cannizzaro Hospital, University of Catania
- Salomone Di Saverio
- Department of Surgery, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust
- Irina M. Dumitru
- Clinical Infectious Diseases Hospital, Ovidius University
- Christian Eckmann
- Department of General, Visceral and Thoracic Surgery, Klinikum Peine, Hospital of Medical University Hannover
- Edward H. Eiland
- Vital Care, Inc
- Joseph D. Forrester
- Department of Surgery, Stanford University
- Gustavo P. Fraga
- Division of Trauma Surgery, Hospital de Clinicas, School of Medical Sciences, University of Campinas
- Jean L. Frossard
- Service of Gastroenterology and Hepatology, Geneva University Hospital
- Donald E. Fry
- Department of Surgery, Northwestern University Feinberg School of Medicine
- Rita Galeiras
- Critical Care Unit, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC)
- Wagih Ghnnam
- Department of Surgery Mansoura, Faculty of Medicine, Mansoura University
- Carlos A. Gomes
- Surgery Department, Hospital Universitario (HU) Terezinha de Jesus da Faculdade de Ciencias Medicas e da Saude de Juiz de Fora (SUPREMA), Hospital Universitario (HU) Universidade Federal de Juiz de Fora (UFJF)
- Ewen A. Griffiths
- Department of Surgery, Queen Elizabeth Hospital
- Xavier Guirao
- Unit of Endocrine, Head, and Neck Surgery and Unit of Surgical Infections Support, Department of General Surgery, Parc Taulí, Hospital Universitari
- Mohamed H. Ahmed
- Department of Medicine, Milton Keynes University Hospital NHS Foundation Trust
- Torsten Herzog
- Department of Surgery, St. Josef Hospital, Ruhr University Bochum
- Jae Il Kim
- Department of Surgery, Ilsan Paik Hospital, Inje University College of Medicine
- Tariq Iqbal
- Department of Gastroenterology, Queen Elizabeth Hospital
- Arda Isik
- General Surgery Department, Magee Womens Hospital, UPMC
- Kamal M. F. Itani
- Department of Surgery, VA Boston Health Care System, Boston University and Harvard Medical School
- Francesco M. Labricciosa
- Global Alliance for Infections in Surgery
- Yeong Y. Lee
- School of Medical Sciences, University Sains Malaysia
- Paul Juang
- Department of Pharmacy Practice, St Louis College of Pharmacy
- Aleksandar Karamarkovic
- Faculty of Mediine University of Belgrade Clinic for Surgery “Nikola Spasic”, University Clinical Center “Zvezdara” Belgrade
- Peter K. Kim
- Department of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine
- Yoram Kluger
- Department of General Surgery, Rambam Health Care Campus
- Ari Leppaniemi
- Abdominal Center, Helsinki University Hospital Meilahti
- Varut Lohsiriwat
- Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University
- Gustavo M. Machain
- Department of Surgery, Universidad Nacional de Asuncion
- Sanjay Marwah
- Department of Surgery, Post-Graduate Institute of Medical Sciences
- John E. Mazuski
- Department of Surgery, Washington University School of Medicine
- Gokhan Metan
- Department of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine
- Ernest E. Moore
- Department of Surgery, University of Colorado, Denver Health Medical Center
- Frederick A. Moore
- Department of Surgery, University of Florida
- Carlos A. Ordoñez
- Department of Surgery, Fundación Valle del Lili, Hospital Universitario del Valle, Universidad del Valle
- Leonardo Pagani
- Infectious Diseases Unit, Bolzano Central Hospital
- Nicola Petrosillo
- National Institute for Infectious Diseases - INMI - Lazzaro Spallanzani IRCCS
- Francisco Portela
- Gastroenterology Department, Centro Hospitalar e Universitário de Coimbra
- Kemal Rasa
- Department of Surgery, Anadolu Medical Center
- Miran Rems
- Department of Abdominal and General Surgery, General Hospital Jesenice
- Boris E. Sakakushev
- Department of Surgery, Medical University of Plovdiv
- Helmut Segovia-Lohse
- Department of Surgery, Universidad Nacional de Asuncion
- Gabriele Sganga
- Division of Emergency Surgery, Department of Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS
- Vishal G. Shelat
- Department of Surgery, Tan Tock Seng Hospital
- Patrizia Spigaglia
- Department of Infectious Diseases, Istituto Superiore di Sanità
- Pierre Tattevin
- Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital
- Cristian Tranà
- Department of Surgery, Macerata Hospital
- Libor Urbánek
- First Department of Surgery, Faculty of Medicine, Masaryk University Brno and University Hospital of St. Ann Brno
- Jan Ulrych
- First Department of Surgery, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague
- Pierluigi Viale
- Clinic of Infectious Diseases, St Orsola-Malpighi University Hospital
- Gian L. Baiocchi
- Department of Clinical and Experimental Sciences, University of Brescia
- Fausto Catena
- Emergency Surgery Department, Maggiore Parma Hospital
- DOI
- https://doi.org/10.1186/s13017-019-0228-3
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 29
Abstract
Abstract In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical patients. Therefore, prevention of CDI and optimization of management in the surgical patient are paramount. An international multidisciplinary panel of experts from the World Society of Emergency Surgery (WSES) updated its guidelines for management of CDI in surgical patients according to the most recent available literature. The update includes recent changes introduced in the management of this infection.
Keywords
- Clostridioides difficile infection
- Clostridium difficile infection
- Pseudomembranous colitis
- Antimicrobial treatment
- Fecal microbiota transplantation
- Infection control
