POLYMORPHISM OF CHRONIC GLOMERULONEPHRITIS ASSOCIATION WITH ADPRT1 GENE VAL762ALA

E. S. Kamyshova; M. Yu. Shvetsov; A. E. Shestakov; I. M. Kutyrina; V. V. Nosikov

doi:10.18786/2072-0505-2014-30-32-36

Alʹmanah Kliničeskoj Mediciny (Feb 2016)

POLYMORPHISM OF CHRONIC GLOMERULONEPHRITIS ASSOCIATION WITH ADPRT1 GENE VAL762ALA

E. S. Kamyshova,
M. Yu. Shvetsov,
A. E. Shestakov,
I. M. Kutyrina,
V. V. Nosikov

Affiliations

E. S. Kamyshova: I.M. Sechenov First Moscow State Medical University
M. Yu. Shvetsov: I.M. Sechenov First Moscow State Medical University
A. E. Shestakov: Clinicodiagnostic Laboratory FimedLab
I. M. Kutyrina: I.M. Sechenov First Moscow State Medical University
V. V. Nosikov: State Research Institute of Genetics and Selection of Industrial Microorganisms GNIIGENETIKA

DOI: https://doi.org/10.18786/2072-0505-2014-30-32-36
Journal volume & issue: Vol. 0, no. 30
pp. 32 – 36

Abstract

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Association of polymorphic ADPRT1 gene Val762Ala marker, encoding poly(ADP-ribose)polymerase-l, with the development, course and progress of chronic glomerulonephritis was revealed during investigation. The risk of the chronic glomerulonephritis development is higher in patients-carriers of Val-allele and Val/Val-genotype and lower in those with Ala-allele and Ala/Ala-genotype.

Published in Alʹmanah Kliničeskoj Mediciny

ISSN: 2072-0505 (Print); 2587-9294 (Online)
Publisher: MONIKI
Country of publisher: Russian Federation
LCC subjects: Medicine
Website: http://www.almclinmed.ru

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