Apoptosis in immune-mediated diseases

Abstract

Apoptosis plays a significant role in both the physiological and pathological process. A dysfunctional apoptotic system can lead to either excessive removal or prolonged survival of cells. Therefore, dysregulation is involved in the pathogenesis of a variety of immunological diseases. The present review aims to provide an overview regarding role of apoptosis in immune-mediated disease.

Keywords

• Apoptosis
• erythema multiforme
• immune mediation
• lichen planus
• Systemic lupus erythematosis