Nature Communications (Mar 2018)

A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons

  • Erik Södersten,
  • Konstantinos Toskas,
  • Vilma Rraklli,
  • Katarina Tiklova,
  • Åsa K. Björklund,
  • Markus Ringnér,
  • Thomas Perlmann,
  • Johan Holmberg

DOI
https://doi.org/10.1038/s41467-018-03538-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 16

Abstract

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The limited size of some neuronal types and their entangled environment renders it difficult to study their transcription regulation. Here the authors present a comparative analysis of histone modifications and transcription in dopaminergic and serotonergic neurons and embryonic neural progenitors.