Nature Communications (Oct 2017)
Anomeric memory of the glycosidic bond upon fragmentation and its consequences for carbohydrate sequencing
Abstract
Establishing generic carbohydrate sequencing methods is both a major scientific challenge and a strategic priority. Here the authors show a hybrid analytical approach integrating molecular spectroscopy and mass spectrometry to resolve carbohydrate isomerism, anomeric configuration, regiochemistry and stereochemistry.