Communications Biology (Oct 2022)

Loss of E-cadherin is causal to pathologic changes in chronic lung disease

  • Baishakhi Ghosh,
  • Jeffrey Loube,
  • Shreeti Thapa,
  • Hurley Ryan,
  • Erin Capodanno,
  • Daniel Chen,
  • Carter Swaby,
  • Si Chen,
  • Saborny Mahmud,
  • Mirit Girgis,
  • Kristine Nishida,
  • Linyan Ying,
  • Pratulya Pragadaraju Chengala,
  • Ethan Tieng,
  • Michael Burnim,
  • Ara Wally,
  • Debarshi Bhowmik,
  • Michael Zaykaner,
  • Bonnie Yeung-Luk,
  • Wayne Mitzner,
  • Shyam Biswal,
  • Venkataramana K. Sidhaye

DOI
https://doi.org/10.1038/s42003-022-04150-w
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 14

Abstract

Read online

Specific loss of the adherens junction protein E-cadherin in alveolar epithelial and airway ciliated cells causes chronic lung disease.