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ACS Central Science
(May 2024)
DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders
Melissa Lim,
Thang Do Cong,
Lauren M. Orr,
Ethan S. Toriki,
Andrew C. Kile,
James W. Papatzimas,
Elijah Lee,
Yihan Lin,
Daniel K. Nomura
Affiliations
Melissa Lim
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
Thang Do Cong
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
Lauren M. Orr
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
Ethan S. Toriki
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
Andrew C. Kile
Novartis-Berkeley Translational Chemical Biology Institute, Berkeley, California, United States
James W. Papatzimas
Novartis-Berkeley Translational Chemical Biology Institute, Berkeley, California, United States
Elijah Lee
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
Yihan Lin
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
Daniel K. Nomura
Department of Chemistry, University of California, Berkeley, Berkeley, California, United States
DOI
https://doi.org/10.1021/acscentsci.4c00286
Journal volume & issue
Vol. 10, no. 7
pp. 1318 – 1331
Abstract
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