Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus

Abstract

Background: This study aimed to explore the effect of 5-HT1A receptors (HTR1A) on activation of the anterior cingulate cortex and simultaneous regulation of neural activity in the insular cortex and hippocampus.

Keywords

• irritable bowel syndrom
• visceral hypersensitivity
• 5-ht1a receptor
• central nervous system
• limbic system