BMC Infectious Diseases (Dec 2005)

<it>Coxiella burnetii </it>vascular graft infection

  • Von Segesser Ludwig,
  • Moulin Alexandre,
  • Raoult Didier,
  • Franciolli Mario,
  • Senn Laurence,
  • Calandra Thierry,
  • Greub Gilbert

DOI
https://doi.org/10.1186/1471-2334-5-109
Journal volume & issue
Vol. 5, no. 1
p. 109

Abstract

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Abstract Background Coxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections. Very few cases of C. burnetii infection of a vascular graft have been reported. All were diagnosed by serology. Case presentation We report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection. Conclusion C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. Broad-range PCR should be performed on culture-negative surgical samples in patients with suspected infection of vascular graft.