Frontiers in Veterinary Science (Sep 2023)

Comparison of standard T2-weighted turbo spin echo and volumetric interpolated breath-hold examination magnetic resonance imaging sequences in the assessment of articular process dysplasia in Pug dogs with thoracolumbar myelopathy

  • Emma Gilbert,
  • Jeremy Rose,
  • Lorna Arrol,
  • Colin J. Driver

DOI
https://doi.org/10.3389/fvets.2023.1265665
Journal volume & issue
Vol. 10

Abstract

Read online

IntroductionA retrospective study to compare the classification, as normal, hypoplastic or aplastic, of thoracic (T10-T13) caudal articular process (CAP) morphology in Pug dogs with a thoracolumbar myelopathy as normal, hypoplastic or aplastic, between T2 weighted Turbo Spin Echo (T2W-TSE), in sagittal and transverse planes, and Volumetric Interpolated Breath-hold Examination (VIBE) Magnetic Resonance Imaging (MRI) sequences, in comparison to Computed Tomography (CT). We hypothesized a stronger agreement for VIBE in comparison to T2W-TSE.ResultsDiagnostic accuracy of T2W-TSE was inferior to VIBE for aplastic (60%, 95% CI 0.561–0.639 vs. 78%, 95%CI 0.744–0.815) hypoplastic (44%, 95%CI 0.427–0.452 vs. 62.5%, 95%CI 0.595–0.655) and normal CAP (70%, 95%CI 0.655–0.744 vs. 87%, 95%CI 0.848–0.892). Superior accuracy of classification using VIBE vs. T2W-TSE sequences using the McNemar Chi squared test was significant for aplastic (p = 0.0002) and normal CAP (p = 0.004). VIBE sequences had a sensitivity of 96% and specificity of 75% to detect CAP abnormality and with T2W-TSE imaging sensitivity 81% and specificity of 75%.DiscussionThree-dimensionally reconstructable VIBE sequences were significantly more accurate than traditional T2W-TSE MRI sequences in classifying CAP morphology, which should reduce the need for CT for pre-operative assessment.

Keywords