Nature Communications (Feb 2023)
The gut microbiome and early-life growth in a population with high prevalence of stunting
- Ruairi C. Robertson,
- Thaddeus J. Edens,
- Lynnea Carr,
- Kuda Mutasa,
- Ethan K. Gough,
- Ceri Evans,
- Hyun Min Geum,
- Iman Baharmand,
- Sandeep K. Gill,
- Robert Ntozini,
- Laura E. Smith,
- Bernard Chasekwa,
- Florence D. Majo,
- Naume V. Tavengwa,
- Batsirai Mutasa,
- Freddy Francis,
- Joice Tome,
- Rebecca J. Stoltzfus,
- Jean H. Humphrey,
- Andrew J. Prendergast,
- Amee R. Manges
Affiliations
- Ruairi C. Robertson
- Blizard Institute, Queen Mary University of London
- Thaddeus J. Edens
- Devil’s Staircase Consulting
- Lynnea Carr
- Department of Microbiology and Immunology, University of British Columbia
- Kuda Mutasa
- Zvitambo Institute for Maternal and Child Health Research
- Ethan K. Gough
- Department of International Health, Johns Hopkins Bloomberg School of Public Health
- Ceri Evans
- Blizard Institute, Queen Mary University of London
- Hyun Min Geum
- School of Population and Public Health, University of British Columbia
- Iman Baharmand
- School of Population and Public Health, University of British Columbia
- Sandeep K. Gill
- School of Population and Public Health, University of British Columbia
- Robert Ntozini
- Zvitambo Institute for Maternal and Child Health Research
- Laura E. Smith
- Zvitambo Institute for Maternal and Child Health Research
- Bernard Chasekwa
- Zvitambo Institute for Maternal and Child Health Research
- Florence D. Majo
- Zvitambo Institute for Maternal and Child Health Research
- Naume V. Tavengwa
- Zvitambo Institute for Maternal and Child Health Research
- Batsirai Mutasa
- Zvitambo Institute for Maternal and Child Health Research
- Freddy Francis
- Department of Experimental Medicine, University of British Columbia
- Joice Tome
- Zvitambo Institute for Maternal and Child Health Research
- Rebecca J. Stoltzfus
- Goshen College, Goshen
- Jean H. Humphrey
- Department of International Health, Johns Hopkins Bloomberg School of Public Health
- Andrew J. Prendergast
- Blizard Institute, Queen Mary University of London
- Amee R. Manges
- School of Population and Public Health, University of British Columbia
- DOI
- https://doi.org/10.1038/s41467-023-36135-6
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 15
Abstract
Here, using metagenomics, the authors show that the gut microbiome of rural Zimbabwean infants undergoes programmed maturation that is unresponsive to sanitation and nutrition interventions but is strongly associated with maternal HIV infection and can moderately predict linear growth.