Nature Communications (Feb 2023)

The gut microbiome and early-life growth in a population with high prevalence of stunting

  • Ruairi C. Robertson,
  • Thaddeus J. Edens,
  • Lynnea Carr,
  • Kuda Mutasa,
  • Ethan K. Gough,
  • Ceri Evans,
  • Hyun Min Geum,
  • Iman Baharmand,
  • Sandeep K. Gill,
  • Robert Ntozini,
  • Laura E. Smith,
  • Bernard Chasekwa,
  • Florence D. Majo,
  • Naume V. Tavengwa,
  • Batsirai Mutasa,
  • Freddy Francis,
  • Joice Tome,
  • Rebecca J. Stoltzfus,
  • Jean H. Humphrey,
  • Andrew J. Prendergast,
  • Amee R. Manges

DOI
https://doi.org/10.1038/s41467-023-36135-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 15

Abstract

Read online

Here, using metagenomics, the authors show that the gut microbiome of rural Zimbabwean infants undergoes programmed maturation that is unresponsive to sanitation and nutrition interventions but is strongly associated with maternal HIV infection and can moderately predict linear growth.