Being elderly is not a contraindication of parathyroidectomy for renal hyperparathyroidism and chronic kidney disease-mineral and bone disorder

Abstract

Summary: Background: Chronic kidney disease-mineral and bone disorder (CKD-MBD) has more influence in the elderly. Parathyroidectomy remains the golden standard for this situation but has tended to be excluded for older patients for many reasons. This study aimed to evaluate the efficacy and safety of the surgery in the elderly population. Methods: 156 patients were included and arranged into younger (≦65 years of age, n = 139) and elderly (>65 years of age, n = 17) groups. The change of bone mineral density (BMD) data, recovery potential {[(postoperative BMD) – (preoperative BMD)]/(preoperative BMD) ∗ 100%}, surgical successful rate and related complications were collected. Results: Both groups exhibited significant postoperative improvement on the BMD results. The recovery potential of the elderly was not lower than the younger group. High success rate and none of persistent vocal palsy, hypocalcemia or any sequela were also observed in the elderly. Conclusions: Parathyroidectomy is an effective and safe intervention for the CKD-MBD in the elderly.

Keywords

• Chronic kidney disease-mineral and bone disorder
• Parathyroidectomy
• Bone mineral density
• Geriatric
• Osteoporosis
• Hypocalcemia