Environmental Factors That Influence Stem Cell Migration: An “Electric Field”

Stephanie N. Iwasa; Robart Babona-Pilipos; Cindi M. Morshead

doi:10.1155/2017/4276927

Stem Cells International (Jan 2017)

Environmental Factors That Influence Stem Cell Migration: An “Electric Field”

Stephanie N. Iwasa,
Robart Babona-Pilipos,
Cindi M. Morshead

Affiliations

Stephanie N. Iwasa: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3E1, Canada
Robart Babona-Pilipos: Department of Surgery, University of Toronto, Toronto, ON, M5S 3E1, Canada
Cindi M. Morshead: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3E1, Canada

DOI: https://doi.org/10.1155/2017/4276927
Journal volume & issue: Vol. 2017

Abstract

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Environmental Stimulus of Electric Fields on Stem Cell Migration. The movement of cells in response to electric potential gradients is called galvanotaxis. In vivo galvanotaxis, powered by endogenous electric fields (EFs), plays a critical role during development and wound healing. This review aims to provide a perspective on how stem cells transduce EFs into directed migration and an understanding of the current literature relating to the mechanisms by which cells sense and transduce EFs. We will comment on potential EF-based regenerative medicine therapeutics.

Published in Stem Cells International

ISSN: 1687-966X (Print); 1687-9678 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine
Website: https://onlinelibrary.wiley.com/journal/4162

About the journal