Association between adipokines and the development of osteopenic syndrome in end-stage lung disease

Abstract

AIM: To study of an association between adipokines, nutritional status, and bone mineral density (BMD) in end-stage lung disease (ESLD). /MATERIAL AND METHODS: Forty-seven patients aged 26 to 62 years with ESLD were examined. BMD in the lumbar spine (LII-LIV) and left femoral neck (FN) was estimated using dual-energy X-ray absorptiometry (DXA). The serum levels of adipokines (leptin, adiponectin resistin, tumor necrosis factor-α (TNF-α), and its receptors sTNFR I, II) were determined. A control group consisted of 45 healthy volunteers matched for age and gender /RESULTS: Osteopenic syndrome (T-score

Keywords

• osteoporosis
• adipokines
• lung disease
• tumor necrosis factor-α
• leptin
• adiponectin