Young adult-born neurons improve odor coding by mitral cells

H. Shani-Narkiss; A. Vinograd; I. D. Landau; G. Tasaka; N. Yayon; S. Terletsky; M. Groysman; I. Maor; H. Sompolinsky; A. Mizrahi

doi:10.1038/s41467-020-19472-8

Nature Communications (Nov 2020)

Young adult-born neurons improve odor coding by mitral cells

H. Shani-Narkiss,
A. Vinograd,
I. D. Landau,
G. Tasaka,
N. Yayon,
S. Terletsky,
M. Groysman,
I. Maor,
H. Sompolinsky,
A. Mizrahi

Affiliations

H. Shani-Narkiss: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
A. Vinograd: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
I. D. Landau: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
G. Tasaka: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
N. Yayon: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
S. Terletsky: Department of Neurobiology, The Hebrew University of Jerusalem
M. Groysman: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
I. Maor: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
H. Sompolinsky: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
A. Mizrahi: The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem

DOI: https://doi.org/10.1038/s41467-020-19472-8
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 16

Abstract

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Shani-Narkiss et al. established an experimental system to test the functional role of adult born neurons (ABNs) on Mitral Cell (MC) coding. Silencing ABNs, unexpectedly, quenched MC odor responses. A computational model provides a mechanistic explanation to the functional role of adult-born neurons in circuit computation of the olfactory bulb.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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