NICHE OF THIRD GENERATION CEPHALOSPORINS IN TREATMENT OF ACUTE BACTERIAL UPPER RESPIRATORY TRACT AND EAR INFECTIONS

Abstract

The vast majority of acute respiratory infections have a viral etiology. Streptococcus pneumoniae, Hemophilus influenza and Moraxella catarrhalis are the major bacterial pathogens responsible for the development of acute sinusitis and acute otitis media. The article presents clinical signs of bacterial paranasal sinuses and ear infections and indications for systemic antibacterial therapy. The issues of choice of antibacterial drugs for the treatment of acute bacterial sinusitis and acute otitis media are reviewed. The niche of third generation cephalosporins in the treatment of this pathology is also examined in this article. The article provides an overview of clinical trials of the efficacy and safety of cefixime in patients with URT and ear diseases.

Keywords

• acute otitis media
• acute bacterial sinusitis
• streptococcus pneumoniae
• hemophilus influenza
• moraxella catarrhalis
• antibiotic therapy