Journal of Clinical Medicine (Aug 2024)

Endoscopic Management of Strictures in Crohn’s Disease: An Unsolved Case

  • Gaetano Coppola,
  • Chiara Principessa,
  • Federica Di Vincenzo,
  • Pierluigi Puca,
  • Angelo Del Gaudio,
  • Ivan Capobianco,
  • Bianca Bartocci,
  • Alfredo Papa,
  • Giovanni Cammarota,
  • Loris Riccardo Lopetuso,
  • Franco Scaldaferri

DOI
https://doi.org/10.3390/jcm13164842
Journal volume & issue
Vol. 13, no. 16
p. 4842

Abstract

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Crohn’s disease (CD) is a chronic inflammatory disease associated with a significant burden in terms of quality of life and health care costs. It is frequently associated with several complications, including the development of intestinal strictures. Stricturing CD requires a careful multidisciplinary approach involving medical therapy and surgery, still posing a continuous management challenge; in this context, endoscopic treatment represents a valuable, in-between opportunity as a minimally invasive strategy endorsed by extensive yet heterogeneous evidence and evolving research and techniques. This review summarizes current knowledge on the role of therapeutic endoscopy in stricturing CD, focusing on evidence gaps, recent updates, and novel techniques intended for optimizing efficacy, safety, and tailoring of this approach in the view of precision endoscopy.

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