Communications Biology (Jan 2023)
An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer
- Richard J. Lobb,
- Kekoolani S. Visan,
- Li-Ying Wu,
- Emma L. Norris,
- Marcus L. Hastie,
- Sarah Everitt,
- Ian A. Yang,
- Rayleen V. Bowman,
- Shankar Siva,
- Jill E. Larsen,
- Jeffrey J. Gorman,
- Michael MacManus,
- Antoine Leimgruber,
- Kwun M. Fong,
- Andreas Möller
Affiliations
- Richard J. Lobb
- Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute
- Kekoolani S. Visan
- Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute
- Li-Ying Wu
- Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute
- Emma L. Norris
- Protein Discovery Centre, QIMR Berghofer Medical Research Institute
- Marcus L. Hastie
- Protein Discovery Centre, QIMR Berghofer Medical Research Institute
- Sarah Everitt
- Department of Radiation Oncology, Peter MacCallum Cancer Centre
- Ian A. Yang
- UQ Thoracic Research Centre, The University of Queensland
- Rayleen V. Bowman
- UQ Thoracic Research Centre, The University of Queensland
- Shankar Siva
- Department of Radiation Oncology, Peter MacCallum Cancer Centre
- Jill E. Larsen
- Faculty of Medicine, University of Queensland
- Jeffrey J. Gorman
- Protein Discovery Centre, QIMR Berghofer Medical Research Institute
- Michael MacManus
- Department of Radiation Oncology, Peter MacCallum Cancer Centre
- Antoine Leimgruber
- Swiss Medical Network
- Kwun M. Fong
- UQ Thoracic Research Centre, The University of Queensland
- Andreas Möller
- Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute
- DOI
- https://doi.org/10.1038/s42003-022-04350-4
- Journal volume & issue
-
Vol. 6,
no. 1
pp. 1 – 9
Abstract
EMT-induced protein changes in small extracellular vesicles are detectable in NSCLC patients and have prognostic significance.
