Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

Abstract

Abstract In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.

Keywords

• Asthma
• Airway epithelium
• Inflammation
• Microarray