Fast microwave heating-based one-step synthesis of DNA and RNA modified gold nanoparticles

Mengqi Huang; Erhu Xiong; Yan Wang; Menglu Hu; Huahua Yue; Tian Tian; Debin Zhu; Hong Liu; Xiaoming Zhou

doi:10.1038/s41467-022-28627-8

Nature Communications (Feb 2022)

Fast microwave heating-based one-step synthesis of DNA and RNA modified gold nanoparticles

Mengqi Huang,
Erhu Xiong,
Yan Wang,
Menglu Hu,
Huahua Yue,
Tian Tian,
Debin Zhu,
Hong Liu,
Xiaoming Zhou

Affiliations

Mengqi Huang: School of Life Sciences, South China Normal University
Erhu Xiong: School of Life Sciences, South China Normal University
Yan Wang: Key Laboratory of Theoretical Chemistry of Environment Ministry of Education, School of Chemistry, South China Normal University
Menglu Hu: School of Life Sciences, South China Normal University
Huahua Yue: School of Life Sciences, South China Normal University
Tian Tian: School of Life Sciences, South China Normal University
Debin Zhu: Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, School of Chemistry, South China Normal University
Hong Liu: Key Laboratory of Theoretical Chemistry of Environment Ministry of Education, School of Chemistry, South China Normal University
Xiaoming Zhou: School of Life Sciences, South China Normal University

DOI: https://doi.org/10.1038/s41467-022-28627-8
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 14

Abstract

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Simple methods for attaching polynucleotides to gold nanoparticles are of interest for simplifying conjugation in a range of applications. Here, the authors report a microwave heating-based method for the fast, one-step attachment of a range of thiolated or non-thiolated DNA and RNA to gold nanoparticles.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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