Conditioned risk factors in patients with coronary heart disease

Abstract

Objective Coronary artery disease (CAD) risk factors are increasing in our country. The present study was performed to determine the prevalence of new (conditioned) risk factors among patients with CAD. Methods In 85 patients with ischemic heart disease (IHD) we study the presence of risk factors including plasma fibrinogen, serum ferritin, serum iron and serum uric acid. The diagnosis of IHD in these patients depends on clinical history and examination, ECG, cardiac echo, and certain investigations including cardiac enzymes. Of these 85 patients, there are 23 females and 62 males, and also there were 50 persons selected as control group. We divided the patients into two groups: one group who had acute coronary heart disease (55 patients) and the second group with chronic IHD (30 patients). Results The result of the study showed that there were statistically significant differences in the level of plasma fibrinogen between the two groups which were higher in the acute group, similar was the case with serum ferritin and serum iron but the level of serum uric acid was the same in both the groups. Conclusion We conclude that plasma fibrinogen and serum ferritin can be used as a marker for the prediction of the presence of acute IHD.

Keywords

• ischemic heart disease , plasma fibrinogen, serum ferritin, uric acid