Proteoglycan-depleted regions of annular injury promote nerve ingrowth in a rabbit disc degeneration model

Affiliations

Xin Long: Department of Spine Surgery, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Xu Weixin: Department of Spine Surgery, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Wang Jian: Department of Spine Surgery, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Yu Fang: Department of Spine Surgery, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Fan Shunwu: Department of Spine Surgery, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310020, Zhejiang Province, China
Xu Xinwei: Department of Spine Surgery, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang Province, China
Yang Yang: Department of Spine Surgery, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou 310012, Zhejiang Province, China

Abstract

To assess the effects of proteoglycan-depleted regions of annular disruptions on nerve ingrowth in the injury site in vivo.