Diagnostics (Jun 2024)

Predictive Factors of Immunotherapy in Gastric Cancer: A 2024 Update

  • Vasile Bintintan,
  • Claudia Burz,
  • Irena Pintea,
  • Adriana Muntean,
  • Diana Deleanu,
  • Iulia Lupan,
  • Gabriel Samasca

DOI
https://doi.org/10.3390/diagnostics14121247
Journal volume & issue
Vol. 14, no. 12
p. 1247

Abstract

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Many studies on gastric cancer treatment have identified predictors of immunotherapy benefits. This article provides an update on the major developments in research related to predictive factors of immunotherapy for gastric cancer. We used the search term “predictive factors, immunotherapy, gastric cancer” to find the most current publications in the PubMed database related to predictive factors of immunotherapy in gastric cancer. Programmed cell death, genetic, and immunological factors are the main study topics of immunotherapy’s predictive factors in gastric cancer. Other preventive factors for immunotherapy in gastric cancer were also found, including clinical factors, tumor microenvironment factors, imaging factors, and extracellular factors. Since there is currently no effective treatment for gastric cancer, we strongly propose that these studies be prioritized.

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