Optimizing Mannose “Click” Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages

• Evan B. Glass,
• Shirin Masjedi,
• Stephanie O. Dudzinski,
• Andrew J. Wilson,
• Craig L. Duvall,
• Fiona E. Yull,
• Todd D. Giorgio

Affiliations

Evan B. Glass

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States

Shirin Masjedi

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States

Stephanie O. Dudzinski

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States

Andrew J. Wilson

Department of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, United States

Craig L. Duvall

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States

Fiona E. Yull

‡Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, United States

Todd D. Giorgio

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States