Trends in antimicrobial use and hospital infection incidence among inpatients

SUN Yiwen; YAN Sijin; LU Feng; FU Xiaofang; SHEN Ruihong; YUAN Yayun; CAI Bingchao; YANG Ya; HUANG Mei; BAN Haiqun

doi:10.19428/j.cnki.sjpm.2024.23615

Shanghai yufang yixue (May 2024)

Trends in antimicrobial use and hospital infection incidence among inpatients

SUN Yiwen,
YAN Sijin,
LU Feng,
FU Xiaofang,
SHEN Ruihong,
YUAN Yayun,
CAI Bingchao,
YANG Ya,
HUANG Mei,
BAN Haiqun

Affiliations

SUN Yiwen: Faculty of Medicine, School of Public Health,University of Sydney, Sydney 2006, Australia
YAN Sijin: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
LU Feng: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
FU Xiaofang: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
SHEN Ruihong: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
YUAN Yayun: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
CAI Bingchao: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
YANG Ya: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
HUANG Mei: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
BAN Haiqun: Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China

DOI: https://doi.org/10.19428/j.cnki.sjpm.2024.23615
Journal volume & issue: Vol. 36, no. 5
pp. 491 – 496

Abstract

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ObjectiveTo understand the use of antibiotics in inpatients and the incidence and trend of hospital infections， to explore the implementation effect of comprehensive management measures， and to provide reference for hospitals to use antibiotics reasonably.MethodsBased on the hospital infection monitoring and management system， a retrospective analysis and comparison were conducted on the use of antibiotics， submission of microbial test samples， and incidence of hospital infections among inpatients in a tertiary hospital from 2012 to 2021.ResultsFrom 2012 to 2021， the use of antibiotics showed a downward trend， from 50.82% in 2012 to 41.29% in 2021. At the same time， the use rate of restricted and special antibiotics had also decreased， and the use rate of restricted and special antibiotics in patients without hospital infection was significantly lower than that in patients with hospital infection， and the microbial testing rate was also on the rise. The annual incidence rate of hospital infection was 0.69%‒1.92%， and the annual case-time prevalence rate was 0.79%‒2.17%. The annual average rate of the above two in 10 years was 1.18% and 1.34%， respectively. The results of the exponential smoothing model also showed that the utilization rate of antibiotics was decreasing and the incidence of nosocomial infection was stable.ConclusionLarge general hospitals took comprehensive management measures to strengthen the management of rational use of antibiotics， which led to a decline in the use rate of antibacterial drugs for inpatients and an increase in the rate of microbial examination. At the same time， the overall incidence of hospital infection was relatively stable， suggesting that the comprehensive management measures of antibacterial drugs in hospitals had achieved certain results. The current measures need to be optimized in the future to continuously improve the management level of rational use of antibacterial drugs.

Published in Shanghai yufang yixue

ISSN: 1004-9231 (Print)
Publisher: Shanghai Preventive Medicine Association
Country of publisher: China
LCC subjects: Medicine
Website: http://www.sjpm.org.cn/indexen.htm

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