Novel Approaches to Program Cells to Differentiate into Cardiomyocytes in Myocardial Regeneration

Abstract

With heart failure (HF) being one of the leading causes of hospitalization and death worldwide, multiple stem cell therapies have been attempted to accelerate the regeneration of the infarct zone. Versatile strategies have emerged to establish the cell candidates of cardiomyocyte lineage for regenerative cardiology. This article illustrates critical insights into the emerging technologies, current approaches, and translational promises on the programming of diverse cell types for cardiac regeneration.

Keywords

• heart failure
• cardiac regeneration
• cell programming
• ipsc
• cell technologies