Repeated intravenous administration of hiPSC-MSCs enhance the efficacy of cell-based therapy in tissue regeneration

Affiliations

Si-Jia Sun: Division of Cardiology, Department of Medicine, The First Affiliated Hospital of Soochow University, Soochow University
Fei Li: Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong
Ming Dong: Bioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory
Wei-Hao Liang: Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University
Wing-Hon Lai: Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong
Wai-In Ho: Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong
Rui Wei: Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong
Yan Huang: Anhui Provincial laboratory of inflammatory and immunity disease, Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University
Song-Yan Liao: Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong
Hung-Fat Tse: Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong

Abstract

A combination of repeated systemic infusion and local transplantation of hiPSC-MSCs could enhance regenerative therapies for cardiovascular disease.