Nonalcoholic fatty liver disease: from research success to clinical algorithms

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a comorbidity of diseases of various etiology characterized by a common pathologic phenomenon: fatty infiltration of the liver parenchyma followed by aseptic inflammation and subsequent fibrogenesis. In general practice, primary NAFLD is a valuable early marker of diabetes mellitus type 2 and high cardiovascular risk. It also predicts insulin resistance and type 2 diabetes in patients with morbid general or visceral obesity and metabolic syndrome. Given the clinical and social importance of CVD, early diagnosis and treatment of NAFLD require a joint effort from doctors of all profiles.

Keywords

• неалкогольная жировая болезнь печени
• метаболический синдром
• эпидемиология
• патогенез
• клиника
• терапия
• non-alcoholic fatty liver disease
• metabolic syndrome
• epidemiology
• pathogenesis
• clinical symptoms
• treatment