Nature Communications (Mar 2020)

Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans

  • Kyung-Tae Lee,
  • Joohyeon Hong,
  • Dong-Gi Lee,
  • Minjae Lee,
  • Suyeon Cha,
  • Yu-Gyeong Lim,
  • Kwang-Woo Jung,
  • Areum Hwangbo,
  • Yelin Lee,
  • Shang-Jie Yu,
  • Ying-Lien Chen,
  • Jong-Seung Lee,
  • Eunji Cheong,
  • Yong-Sun Bahn

DOI
https://doi.org/10.1038/s41467-020-15329-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, the authors identify fungal kinases and transcription factors involved in blood-brain barrier crossing and brain infection in mice.