Nature Communications (Jul 2021)

DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination

  • Prasun Chakraborty,
  • Kevin Hiom

DOI
https://doi.org/10.1038/s41467-021-24341-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 18

Abstract

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DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.