Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models

• Jimena Monzón-Sandoval,
• Elena Burlacu,
• Devika Agarwal,
• Adam E. Handel,
• Liting Wei,
• John Davis,
• Sally A. Cowley,
• M. Zameel Cader,
• Caleb Webber

Affiliations

Jimena Monzón-Sandoval

UK Dementia Research Institute, Cardiff University, Cardiff CF24 4HQ, UK

Elena Burlacu

John Radcliffe Hospital, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DS, UK

Devika Agarwal

Nuffield Department of Medicine Research Building, Alzheimer's Research UK Oxford Drug Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK

Adam E. Handel

John Radcliffe Hospital, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DS, UK

Liting Wei

James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK

John Davis

Nuffield Department of Medicine Research Building, Alzheimer's Research UK Oxford Drug Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK

Sally A. Cowley

Translational Molecular Neuroscience Group, New Biochemistry Building, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX1 3QU, UK

M. Zameel Cader

John Radcliffe Hospital, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DS, UK

Caleb Webber

UK Dementia Research Institute, Cardiff University, Cardiff CF24 4HQ, UK