Ru(phen)3Cl2‐Catalyzed Chlorotrifluoromethylation of Unactivated Alkenes

Wenhao Su; Jing Cui; Prof. Dr. Runsheng Zeng

doi:10.1002/open.202300068

ChemistryOpen (Jul 2023)

Ru(phen)3Cl2‐Catalyzed Chlorotrifluoromethylation of Unactivated Alkenes

Wenhao Su,
Jing Cui,
Prof. Dr. Runsheng Zeng

Affiliations

Wenhao Su: Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China
Jing Cui: Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China
Prof. Dr. Runsheng Zeng: Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China

DOI: https://doi.org/10.1002/open.202300068
Journal volume & issue: Vol. 12, no. 7
pp. n/a – n/a

Abstract

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Abstract A novel Ru(phen)3Cl2‐catalyzed free‐radical chlorotrifluoromethylation reaction of unactivated olefins was investigated. Substituted 8‐aminoquinoline‐derived inert enamides were reacted with the Togni regent to afford a broad range of Cl‐containing trifluoromethyl derivatives in good yields. The reaction proceeded at 90 °C and experimental result shows that the chlorine source of the products originated from LiCl.

Published in ChemistryOpen

ISSN: 2191-1363 (Online)
Publisher: Wiley-VCH
Country of publisher: Germany
LCC subjects: Science: Chemistry
Website: https://chemistry-europe.onlinelibrary.wiley.com/journal/21911363

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