Nature Communications (Nov 2017)

Chromosome segregation occurs by microtubule pushing in oocytes

  • Kimberley Laband,
  • Rémi Le Borgne,
  • Frances Edwards,
  • Marine Stefanutti,
  • Julie C. Canman,
  • Jean-Marc Verbavatz,
  • Julien Dumont

DOI
https://doi.org/10.1038/s41467-017-01539-8
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 11

Abstract

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In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle control chromosomal segregation.