E3S Web of Conferences (Jan 2024)

Optimizing synthesis and applications of sodium valproate: Towards efficiency, affordability, and sustainability

  • Chen Aowen,
  • Su Shengyang

DOI
https://doi.org/10.1051/e3sconf/202455304015
Journal volume & issue
Vol. 553
p. 04015

Abstract

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This study reviews the synthesis, optimization, and potential applications of sodium valproate, a key pharmaceutical agent in the treatment of neurological disorders such as epilepsy, bipolar disorder, and depression. The primary focus is on refining the synthesis process of sodium valproate to enhance production efficiency, reduce costs, and increase the accessibility of this crucial medication. By exploring various synthetic routes and optimizing reaction conditions—such as temperature, pressure, and solvent selection. The study aims to develop a more efficient and cost-effective manufacturing process. Special attention is given to the environmental impacts of the synthesis methods, seeking to establish greener and more sustainable practices. The study also discusses advancements in drug formulations, including the development of new therapeutic indications and combination therapies that could potentially improve patient outcomes. Future research directions include optimizing sodium valproate’s molecular structure, investigating its use in personalized medicine, and minimizing its side effects. Through meticulous analysis and innovative approaches, this research contributes to the ongoing development of sodium valproate, ensuring its efficacy, safety, and environmental sustainability in pharmaceutical production.